Calculate maintenance intravenous fluid rate using the validated Holliday-Segar 4-2-1 formula. Adjust for dehydration, fasting, or surgical scenarios.
EasyClinic auto-calculates maintenance fluids on admission, generates printable IV orders, and tracks total fluid balance across nursing shifts. Built for IPD.
The Holliday-Segar formula (also called the 4-2-1 rule) is the standard method for calculating maintenance intravenous fluid requirements in pediatric and adult patients. Published in 1957 by Drs. Malcolm Holliday and William Segar, it remains the most widely-used IV fluid calculation in hospitals worldwide.
Daily Requirement:
Hourly Rate (4-2-1):
This pediatric and adult IV fluid maintenance calculator is essential for emergency physicians, pediatricians, internists, anesthesiologists, intensivists, and ward nurses managing inpatients across India — from district hospitals in UP and Bihar to tertiary care centres like AIIMS, PGI Chandigarh, CMC Vellore, Apollo, Fortis, Manipal, and Max hospitals.
Common clinical scenarios: post-operative patients, dehydrated children with gastroenteritis, NBM (nil by mouth) pre-procedure patients, septic shock resuscitation, burns, diabetic ketoacidosis (DKA) — though specific protocols (like DKA fluid management) require additional considerations beyond simple maintenance calculation.
Modern evidence (NICE NG29, 2015; updated SPLIT and PLUS trials) recommends isotonic balanced crystalloids (Ringer's Lactate or Plasma-Lyte) over 0.45% saline for routine maintenance to prevent hospital-acquired hyponatremia, especially in children. For pediatric patients, D5 in 0.9% NaCl (D5NS) is now preferred over hypotonic D5 in 0.45% NaCl.
4 mL/kg/hour for the first 10 kg + 2 mL/kg/hour for the next 10 kg + 1 mL/kg/hour for every kg above 20 kg. This gives the maintenance hourly fluid requirement.
Using 4-2-1: 40 (first 10kg) + 20 (next 10kg) + 5 (kg 21-25) = 65 mL/hour. Daily total: 1500 + 100 = 1600 mL/day.
Modern guidelines (NICE NG29, 2015) recommend isotonic balanced crystalloids (Ringer's Lactate) or D5NS for pediatric maintenance to prevent iatrogenic hyponatremia.
For a macrodrip set (15 drops/mL): drops/min = (mL/hr × 15) / 60. For a microdrip pediatric set (60 drops/mL): drops/min = mL/hour directly.
Yes, increase by 10-12% for every 1°C rise above 37°C in sustained fever. Account for insensible losses.
Yes, it works for adults but typically gives 2400-2600 mL/day for a 70kg adult. Most hospitals cap maintenance at ~2400 mL/day in healthy adults.
EasyClinic auto-calculates maintenance fluids on patient admission, suggests appropriate fluid type (RL/NS/D5NS), and tracks total intake/output across nursing shifts.