Galvus (Vildagliptin)
Also sold as: Galvus, Galvus Met (with metformin), Jalra, Vildagrand
Pregnancy
Cat B
Lactation
Avoid
Schedule
H
Forms
Tablet 50mg +1
Indications
- T2DM (mono or add-on)
Adult Dosing
T2DM
50 mg BD (or 100 mg OD)
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| eGFR > 50 | Standard 50 mg BD |
| eGFR < 50 | 50 mg OD |
Hepatic Adjustment
Avoid in hepatic impairment or ALT/AST >3× ULN
Pregnancy & Lactation
Pregnancy: Category B
Lactation: Avoid
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| Insulin/sulfonylureas | Hypoglycemia | Moderate |
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Side Effects
Common
- Nasopharyngitis
- Headache
- Nausea
Serious / Discontinue If
- Pancreatitis
- Hepatotoxicity (specific to vilda — monitor LFT)
- Severe arthralgia
- Bullous pemphigoid
Contraindications
- Hepatic impairment
- Type 1 DM, DKA
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Galvus 50 | Novartis | 14 tab ₹485 |
| Jalra 50 | USV | 14 tab ₹385 |
Monitoring Required
- LFT at baseline, every 3 months × 1 year, then annually
- eGFR
Patient Counseling Points
- Stop and report severe abdominal pain or jaundice
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References
- BNF
- Lexicomp
- Indian National Formulary
- Specialty society guidelines
Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.