Omez (Omeprazole)
Also sold as: Omez, OCID, Omepraz, Lomac
Pregnancy
Cat C
Lactation
Caution
Schedule
OTC
Forms
Capsule 20/40mg +1
Indications
- GERD
- Peptic ulcer
- H. pylori eradication
- NSAID-induced ulcer prophylaxis
- Dyspepsia
Adult Dosing
GERD/PUD
20 mg PO once daily before breakfast
4-8 weeks
H. pylori
20 mg BD with antibiotics × 14 days
Pediatric Dosing
Age Range: >1 year
Dose: 0.5-1 mg/kg/day OD
Max/day: 40 mg/day
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| No adjustment needed | No CrCl-based dose adjustment required |
Hepatic Adjustment
Reduce dose; max 20 mg/day in severe hepatic impairment
Pregnancy & Lactation
Pregnancy: Category C
Lactation: Caution
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| Clopidogrel | AVOID — significantly reduces clopidogrel efficacy. Use pantoprazole instead | Major |
| Diazepam, Phenytoin, Warfarin | Increased levels (CYP2C19 inhibition) | Moderate |
| Iron, ketoconazole | Reduced absorption | Moderate |
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Side Effects
Common
- Headache
- Diarrhea
- Nausea
Serious / Discontinue If
- C. diff colitis
- Hypomagnesemia, B12 deficiency, fractures (long-term)
- Acute interstitial nephritis
Contraindications
- Hypersensitivity
- Co-administration with rilpivirine, atazanavir
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Omez 20 | Dr Reddy's | 15 cap ₹85 |
| OCID 20 | Zydus | 15 cap ₹70 |
| Lomac 20 | Cipla | 15 cap ₹65 |
Patient Counseling Points
- Take before breakfast
- Avoid combining with clopidogrel
- Limit to short courses if possible
Stop Googling drug references mid-consultation
EasyClinic auto-flags Omez interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
References
- BNF
- Lexicomp Drug Information
- Indian National Formulary
- Specialty society guidelines (RSSDI/CSI/IAP)
Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.