Norflox (Norfloxacin)
Also sold as: Norflox, Norbactin, Bactipro, Norfilox
Pregnancy
Cat C
Lactation
Avoid
Schedule
H
Forms
Tablet 200/400mg
Indications
- Uncomplicated UTI (limited use due to FQ restrictions)
- SBP prophylaxis in cirrhosis
- Bacterial diarrhea (Shigella, Salmonella)
- Gonorrhea (alternative)
Adult Dosing
UTI
400 mg PO BD × 3-7 days
SBP prophylaxis
400 mg PO OD
Diarrhea
400 mg PO BD × 3 days
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| CrCl > 30 | Standard |
| CrCl < 30 | 400 mg OD |
Pregnancy & Lactation
Pregnancy: Category C
Avoid
Lactation: Avoid
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| Antacids, iron, calcium | Reduced absorption | Major |
| Theophylline | Toxicity | Major |
| NSAIDs | Seizure risk | Moderate |
| Warfarin | Increased INR | Moderate |
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Side Effects
Common
- Nausea
- Headache
- Photosensitivity
Serious / Discontinue If
- Tendon rupture
- Aortic dissection
- C. diff
- QT prolongation
- Peripheral neuropathy
Contraindications
- Quinolone allergy
- Tendinopathy history
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Norflox 400 | Cipla | 10 tab ₹65 |
| Norbactin 400 | Ranbaxy | 10 tab ₹55 |
Patient Counseling Points
- Take 1h before/2h after food/antacids
- Stop and report tendon pain
- Avoid sun
Stop Googling drug references mid-consultation
EasyClinic auto-flags Norflox interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
References
- BNF
- Lexicomp
- Indian National Formulary
- Specialty society guidelines
Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.