Moxifloxacin (Moxifloxacin)
Also sold as: Avelox, Moxi, Mozix
Pregnancy
Cat C
Lactation
Caution
Schedule
H
Forms
Tablet 400mg +2
Indications
- Community-acquired pneumonia (CAP)
- Acute bacterial sinusitis
- Acute exacerbation of chronic bronchitis
- Complicated skin infections
- Intra-abdominal infections (with metronidazole)
Adult Dosing
CAP/sinusitis/bronchitis
400 mg PO/IV once daily
5-10 days
Complicated skin
400 mg PO/IV once daily
7-21 days
Pediatric Dosing
Tendon rupture and CNS effects in pediatric population
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| CrCl > 30 mL/min | No adjustment |
| CrCl < 30 mL/min / Severe hepatic | Use with caution; no specific dose adjustment but monitor closely |
Hepatic Adjustment
Use with caution in severe hepatic impairment
Pregnancy & Lactation
Pregnancy: Category C
Avoid in pregnancy due to lack of safety data; teratogenic risk unknown.
Lactation: Caution
Likely excreted in breast milk; monitor infant.
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| Antacids/Iron/Calcium | Reduced moxifloxacin absorption (separate by 4 hours) | Major |
| Warfarin | Enhanced anticoagulant effect; monitor INR | Moderate |
| QT-prolonging agents | Risk of QT prolongation and torsades de pointes | Major |
| Diclofenac | Increased CNS stimulation | Moderate |
DoctorScribe — AI Medical Scribe
Stop looking up Moxifloxacin — just speak the prescription
"Moxifloxacin as per dose, BD for 5 days." DoctorScribe writes the full prescription with brand, strength, frequency, and route — auto-applies pediatric weight-based dosing and renal adjustments. Try the live demo.
Side Effects
Common
- Nausea
- Diarrhea
- Dizziness
- Headache
- Photosensitivity
Serious / Discontinue If
- QT prolongation
- Hepatotoxicity (rare)
- Tendon rupture
- Aortic dissection (rare)
- Exfoliative dermatitis
Contraindications
- Myasthenia gravis
- QT prolongation
- Severe hepatic impairment
- Hypersensitivity to fluoroquinolones
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Avelox 400 | Bayer | 5 tab ₹450 |
| Moxi 400 | Cipla | 5 tab ₹320 |
Monitoring Required
- QTc interval
- LFT in prolonged use
- Signs of hepatotoxicity or tendon pain
- Renal function
Patient Counseling Points
- Take 4 hours before/after antacids or iron
- Photosensitivity risk: use sunscreen
- Report jaundice, severe abdominal pain, or tendon symptoms
- Avoid NSAIDs if possible
Stop Googling drug references mid-consultation
EasyClinic auto-flags Moxifloxacin interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
Clinically reviewed by: Dr. Priya Sharma, MD (Pulmonology), CHEST Member
Last reviewed: 2026-04-14
References
- BNF — Moxifloxacin
- IDSA CAP Guidelines 2023
- Bayer Avelox Product Monograph