Meftal (Mefenamic Acid)
Also sold as: Meftal, Ponstan, Mefkind, Medol
Pregnancy
Cat C
Lactation
Caution
Schedule
H
Forms
Tablet 250/500mg +2
Indications
- Dysmenorrhea
- Menorrhagia (reduces blood loss 25%)
- Mild-moderate pain
- Pediatric fever (alternative)
Adult Dosing
Dysmenorrhea
500 mg PO loading, then 250 mg every 6 hours during menses
2-3 days
Pain
250-500 mg PO TDS, max 7 days
Maximum daily dose: 1500 mg/day, max 7 days
Pediatric Dosing
Age Range: >6 months
Dose: 6.5 mg/kg every 6-8 hours
Max/day: 50 mg/kg/day
Limit to 7 days
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| CrCl < 30 | AVOID |
Pregnancy & Lactation
Pregnancy: Category C
Avoid in 3rd trimester
Lactation: Caution
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| Warfarin | Bleeding | Major |
| Lithium, methotrexate | Toxicity | Moderate |
| ACE/ARB/diuretics | AKI | Major |
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Side Effects
Common
- Diarrhea (notable)
- Nausea
- Dyspepsia
- Headache
- Drowsiness
Serious / Discontinue If
- Hemolytic anemia (rare)
- GI bleed
- AKI
- Convulsions in overdose (especially in elderly)
Contraindications
- Active PUD
- Severe CKD/HF
- Hypersensitivity
- IBD
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Meftal 500 | Blue Cross | 15 tab ₹85 |
| Mefkind 250 | Mankind | 10 tab ₹35 |
| Meftal-Spas (with dicyclomine) | Blue Cross | 10 tab ₹75 |
Patient Counseling Points
- Take with food
- Limit to 7 days
- Stop and seek help if diarrhea
Stop Googling drug references mid-consultation
EasyClinic auto-flags Meftal interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
References
- BNF
- Lexicomp
- Indian National Formulary
- Specialty society guidelines
Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.