Etoshine (Etoricoxib)
Also sold as: Etoshine, Nucoxia, Algirex, Etogesic
Pregnancy
Cat C
Lactation
Avoid
Schedule
H
Forms
Tablet 60/90/120mg
Indications
- Osteoarthritis
- RA
- Ankylosing spondylitis
- Acute gout (120mg short-term)
- Acute pain (post-op, dental)
Adult Dosing
OA
30-60 mg PO OD
RA/AS
90 mg PO OD
Acute gout
120 mg PO OD × 8 days max
Maximum daily dose: 120 mg/day
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| CrCl < 30 | AVOID |
Hepatic Adjustment
Mild: max 60 mg OD. Moderate: max 60 mg every other day. Severe: avoid.
Pregnancy & Lactation
Pregnancy: Category C
Avoid in pregnancy
Lactation: Avoid
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| ACE/ARB/diuretics | AKI, reduced effect | Major |
| Warfarin | Less effect than non-selective NSAIDs but monitor | Moderate |
| Lithium, methotrexate | Toxicity | Moderate |
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Side Effects
Common
- Hypertension
- Edema
- Dyspepsia (less than non-selective NSAIDs)
- Headache
Serious / Discontinue If
- Cardiovascular events (avoid in established CVD)
- GI bleed (less but still occurs)
- AKI
- Hepatotoxicity
- Severe skin reactions
Contraindications
- Established CV disease, post-CABG
- Uncontrolled HTN
- Severe HF
- Active PUD
- IBD
- Severe hepatic/renal impairment
- Pregnancy/lactation
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Etoshine 90 | Sun Pharma | 10 tab ₹185 |
| Nucoxia 90 | Zydus | 10 tab ₹165 |
| Algirex 90 | Cipla | 10 tab ₹155 |
Patient Counseling Points
- Take with food (optional)
- Monitor BP regularly
- Avoid if you have heart disease history
- Use lowest effective dose for shortest period
Stop Googling drug references mid-consultation
EasyClinic auto-flags Etoshine interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
References
- BNF
- Lexicomp
- Indian National Formulary
- Specialty society guidelines
Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.