EasyClinic Drug Reference

Indian clinical drug database

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All Drugs

PPI · PPI (S-isomer of omeprazole)

Nexpro (Esomeprazole Magnesium)

Also sold as: Nexpro, Nexium, Sompraz, Esoz

Pregnancy

Cat B

Lactation

Caution

Schedule

Forms

Tablet 20/40mg +1

Indications

GERD (especially erosive)
PUD
H. pylori
Severe symptomatic GERD

Adult Dosing

GERD

20-40 mg PO OD before breakfast

4-8 weeks

Renal Dose Adjustment

CrCl / eGFR	Dose Adjustment
No adjustment needed	No CrCl-based dose adjustment required

Calculate eGFR / CrCl →

Hepatic Adjustment

Max 20 mg/day in severe hepatic impairment

Pregnancy & Lactation

Pregnancy: Category B

Lactation: Caution

Top Drug Interactions

Interacting Drug	Effect	Severity
Clopidogrel	Reduced efficacy — caution	Moderate
Diazepam, citalopram, phenytoin	Increased levels	Moderate

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Side Effects

Common

Headache
Diarrhea
Abdominal pain

Serious / Discontinue If

Same long-term PPI risks as others

Contraindications

Hypersensitivity

Available Indian Brands

Brand	Manufacturer	Price (approx)
Nexpro 40	Torrent	15 tab ₹165
Sompraz 40	Sun Pharma	15 tab ₹185
Esoz 40	Cipla	15 tab ₹155

Patient Counseling Points

Take before breakfast
Try to limit duration

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References

BNF
Lexicomp Drug Information
Indian National Formulary
Specialty society guidelines (RSSDI/CSI/IAP)

Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.