Defcort (Deflazacort)
Also sold as: Defcort, Defza, Calcort
Pregnancy
Cat C
Lactation
Caution
Schedule
H
Forms
Tablet 1/6/30mg +1
Indications
- Same as prednisolone — preferred in some clinics for fewer mineralocorticoid effects
- Duchenne muscular dystrophy
Adult Dosing
Most indications
6-90 mg PO OD (7.5 mg defla = 5 mg pred)
Pediatric Dosing
Age Range: All ages
Dose: 0.25-1.5 mg/kg/day
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| No adjustment needed | No CrCl-based adjustment |
Pregnancy & Lactation
Pregnancy: Category C
Lactation: Caution
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| Same as prednisolone | Same profile | Major |
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Side Effects
Common
- Less weight gain than prednisolone
- Same other steroid effects
Serious / Discontinue If
- Same as prednisolone
Contraindications
- Same as prednisolone
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Defcort 6 | Macleods | 10 tab ₹35 |
| Defza 6 | Sun Pharma | 10 tab ₹38 |
Patient Counseling Points
- Take with food in morning
- Taper after >2 weeks use
- Carry steroid card
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EasyClinic auto-flags Defcort interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
References
- BNF
- Lexicomp
- Indian National Formulary
- Specialty society guidelines
Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.