EasyClinic Drug Reference

Indian clinical drug database

Start Free Trial

All Drugs

Antibiotic · Fluoroquinolone

Ciplox (Ciprofloxacin)

Also sold as: Ciplox, Cifran, Cipro, Quintor

Pregnancy

Cat C

Lactation

Caution

Schedule

Forms

Tablet 250/500/750mg +3

Indications

Complicated UTI / pyelonephritis
Prostatitis
Bacterial gastroenteritis (Shigella, Salmonella)
Typhoid
Anthrax exposure
Pseudomonal infections

Adult Dosing

Uncomplicated UTI

250 mg PO BD

3 days (avoid first-line per IDSA)

Pyelonephritis

500-750 mg PO BD

7-14 days

Bacterial diarrhea

500 mg PO BD

3-5 days

IV (severe)

400 mg IV every 8-12 hours

Maximum daily dose: 1.5 g/day

Pediatric Dosing

Age Range: Generally avoided <18y; reserve for severe infections

Dose: 20-30 mg/kg/day divided BD

Max/day: 1.5 g/day

Risk of arthropathy/tendon rupture. Use only when no alternative.

Renal Dose Adjustment

CrCl / eGFR	Dose Adjustment
CrCl > 50 mL/min	No adjustment
CrCl 30-50 mL/min	250-500 mg every 12 hours
CrCl < 30 mL/min	250-500 mg every 18 hours

Calculate eGFR / CrCl →

Pregnancy & Lactation

Pregnancy: Category C

Avoid in pregnancy — animal studies show cartilage damage. Use alternative.

Lactation: Caution

Top Drug Interactions

Interacting Drug	Effect	Severity
Antacids, iron, calcium, sucralfate	Reduced absorption — separate by 2 hours	Major
Warfarin	Significantly increased INR	Major
Theophylline	Increased theophylline toxicity	Major
NSAIDs	Increased seizure risk	Moderate
QT-prolonging drugs	Additive QT prolongation	Major
Tizanidine	CONTRAINDICATED — severe hypotension/sedation	Major

DoctorScribe — AI Medical Scribe

Stop looking up Ciplox — just speak the prescription

"Ciplox as per dose, BD for 5 days." DoctorScribe writes the full prescription with brand, strength, frequency, and route — auto-applies pediatric weight-based dosing and renal adjustments. Try the live demo.

Try DoctorScribe Demo →Start Free Trial

Side Effects

Common

Nausea, diarrhea
Headache
Dizziness
Photosensitivity
Insomnia

Serious / Discontinue If

Tendon rupture (Achilles, especially with steroids)
Aortic aneurysm/dissection
C. difficile colitis
Peripheral neuropathy
QT prolongation, Torsades
Seizures
Hypoglycemia/hyperglycemia

Contraindications

Quinolone hypersensitivity
Tendinopathy history with quinolones
Co-administration with tizanidine
Pregnancy (relative)

Available Indian Brands

Brand	Manufacturer	Price (approx)
Ciplox 500	Cipla	10 tab ₹35
Cifran 500	Sun Pharma	10 tab ₹38
Quintor 500	Torrent	10 tab ₹32

Monitoring Required

ECG (QT) in at-risk patients
Blood glucose in diabetics
Watch for tendon pain

Patient Counseling Points

Avoid sun exposure
Stop and report any tendon pain immediately
Avoid antacids/iron within 2 hours
Report palpitations

Stop Googling drug references mid-consultation

EasyClinic auto-flags Ciplox interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.

Start 7-Day Free Trial

References

BNF — Ciprofloxacin
FDA Black Box Warning Fluoroquinolones
IDSA UTI Guidelines

Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.