Cetzine (Cetirizine HCl)
Also sold as: Cetzine, Alerid, Hicet, Cetrizet
Pregnancy
Cat B
Lactation
Safe
Schedule
OTC
Forms
Tablet 5/10mg +2
Indications
- Allergic rhinitis (seasonal/perennial)
- Chronic urticaria
- Atopic dermatitis (symptom relief)
- Insect bite reactions
Adult Dosing
All
10 mg PO once daily (preferably at night)
Pediatric Dosing
Age Range: >2 years
Dose: 0.25 mg/kg once daily; 6m-2y: 2.5 mg OD; 2-6y: 5 mg OD; >6y: 10 mg OD
Max/day: 10 mg/day
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| CrCl 30-49 | 5 mg once daily |
| CrCl 10-30 | 5 mg every other day |
| CrCl < 10 | Avoid |
Hepatic Adjustment
Severe: 5 mg once daily
Pregnancy & Lactation
Pregnancy: Category B
Lactation: Safe
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| CNS depressants (alcohol, sedatives) | Additive sedation | Moderate |
| Theophylline | Slightly reduced cetirizine clearance | Minor |
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Side Effects
Common
- Drowsiness (more than other 2nd gen)
- Dry mouth
- Headache
- Fatigue
Serious / Discontinue If
- Severe pruritus on abrupt discontinuation (after long-term use)
- Angioedema (very rare)
Contraindications
- Hypersensitivity to cetirizine or hydroxyzine
- End-stage renal disease (CrCl <10)
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Cetzine 10 | GSK | 10 tab ₹15 |
| Alerid 10 | Cipla | 10 tab ₹18 |
| Hicet 10 | Micro Labs | 10 tab ₹12 |
Patient Counseling Points
- Take at night to minimize daytime drowsiness
- Avoid alcohol
- May taper slowly after long use to avoid rebound itch
Stop Googling drug references mid-consultation
EasyClinic auto-flags Cetzine interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
References
- BNF
- Lexicomp Drug Information
- Indian National Formulary
- Specialty society guidelines (RSSDI/CSI/IAP)
Disclaimer: This information is for clinical reference only. It is not exhaustive and does not substitute clinical judgement. Always verify current dosing against the manufacturer's prescribing information and current treatment guidelines. Drug prices are approximate and may vary.