Atorva (Atorvastatin Calcium)
Also sold as: Atorva, Storvas, Atorlip, Aztor, Lipitor
Pregnancy
Cat X
Lactation
Avoid
Schedule
H
Forms
Tablet 5/10/20/40/80mg +1
Indications
- Primary prevention of CVD (intermediate-high ASCVD risk)
- Secondary prevention (post-MI, stroke, PAD)
- Hyperlipidemia (high LDL)
- Diabetes age 40-75 with LDL 70-189
Adult Dosing
Moderate intensity
10-20 mg PO once daily (any time)
Lifelong typically
High intensity
40-80 mg PO once daily
For ASCVD ≥20%, established CVD, LDL ≥190, diabetes with risk factors
Pediatric Dosing
Specialist initiation for genetic dyslipidemia
Renal Dose Adjustment
| CrCl / eGFR | Dose Adjustment |
|---|---|
| No adjustment | No CrCl-based adjustment for atorvastatin |
Hepatic Adjustment
CONTRAINDICATED in active liver disease or unexplained persistent ALT/AST elevation >3× ULN
Pregnancy & Lactation
Pregnancy: Category X
CONTRAINDICATED — discontinue 3 months before planned conception. Cholesterol essential for fetal development.
Lactation: Avoid
Top Drug Interactions
| Interacting Drug | Effect | Severity |
|---|---|---|
| Clarithromycin, Erythromycin, Itraconazole, Ketoconazole, HIV protease inhibitors | Increased atorvastatin levels — myopathy/rhabdomyolysis risk | Major |
| Cyclosporine | Significantly increased levels — limit atorva to 10 mg | Major |
| Gemfibrozil, Niacin | Increased myopathy risk | Moderate |
| Warfarin | Modest INR increase | Moderate |
| Grapefruit juice (>1.2L/day) | Increased atorva levels | Minor |
| Rifampicin | Reduced atorva levels | Moderate |
DoctorScribe — AI Medical Scribe
Stop looking up Atorva — just speak the prescription
"Atorva as per dose, BD for 5 days." DoctorScribe writes the full prescription with brand, strength, frequency, and route — auto-applies pediatric weight-based dosing and renal adjustments. Try the live demo.
Side Effects
Common
- Myalgia (5-10%)
- GI upset
- Headache
- Mild ALT elevation
- New-onset diabetes (small risk)
Serious / Discontinue If
- Rhabdomyolysis (rare)
- Hepatotoxicity (rare, monitor LFT if symptomatic)
- Immune-mediated necrotizing myopathy
Contraindications
- Active liver disease
- Pregnancy/lactation
- Hypersensitivity
Available Indian Brands
| Brand | Manufacturer | Price (approx) |
|---|---|---|
| Atorva 10 | Zydus | 15 tab ₹85 |
| Storvas 10 | Ranbaxy | 15 tab ₹95 |
| Atorlip 10 | Cipla | 15 tab ₹85 |
| Aztor 10 | Sun Pharma | 10 tab ₹75 |
Monitoring Required
- Lipid profile at 6-12 weeks after starting/dose change
- LFT at baseline; only repeat if symptomatic
- CK only if myalgia
Patient Counseling Points
- Can take any time of day (doesn't require evening dose)
- Report unexplained muscle pain, weakness, dark urine immediately
- Avoid grapefruit
- Continue even when LDL normal — for vascular benefit
Stop Googling drug references mid-consultation
EasyClinic auto-flags Atorva interactions, renal cutoffs, and pregnancy warnings the moment you write the prescription. Built-in safety net for every Indian doctor.
References
- BNF
- Lexicomp Drug Information
- Indian National Formulary
- IAP/RSSDI/CSI Guidelines